Today organizations must be able to gain the necessary knowledge for modernization of their products and improvement of their processes, and also spread this idea among their stuff and apply in their all daily activities. In knowledge-based economy, organizations use knowledge management as an essential factor for better performance and to gain the advantage of competition, and in this respect knowledge management strategies play main part in improvement of organizational performance. This article has studied the effect of knowledge management strategy on organizational performance in companies located in Bandar Abbas Industrial Town. Main goal of this study has been the study of effects of knowledge management strategy on organizational performance in companies located in Bandar Abbas Industrial Town in 1393. In terms of the goal of research this study is an applying study, and in terms of method of data collecting is descriptive-surveying research, and in terms of relation between variables of the study it is of correlation type and specifically is based on structural equations. The tool for collecting data is questionnaire. Statistical population of this study was 475 people of managers, deputies, and middle-rank managers of Bandar Abbas industrial towns, that 212 people were chosen as sample using Morgan table to specify the sample size. Analyzing data was done using community average exam and structural equations model. The findings of this study showed that there was positive and meaningful relation between setting knowledge management and organizational performance in Bandar Abbas Industrial Town.